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FGF13 suppresses acute myeloid leukemia by regulating bone marrow niches
《医学前沿(英文)》 2022年 第16卷 第6期 页码 896-908 doi: 10.1007/s11684-022-0944-z
关键词: acute myeloid leukemia FGF13 prognosis immune-related genes bone marrow niches
Xiaokun Li
《医学前沿(英文)》 2019年 第13卷 第5期 页码 511-530 doi: 10.1007/s11684-019-0711-y
FGF23 associated bone diseases
null
《医学前沿(英文)》 2013年 第7卷 第1期 页码 65-80 doi: 10.1007/s11684-013-0254-6
Recently, fibroblast growth factor 23 (FGF23) has sparked widespread interest because of its potential role in regulating phosphate and vitamin D metabolism. In this review, we summarized the FGF superfamily, the mechanism of FGF23 on phosphate and vitamin D metabolism, and the FGF23 related bone disease.
关键词: fibroblast growth factor 23 FGF receptor phosphate metabolism Klotho bone disease
Influence of retinoic acid on TBX1 expression in myocardial cells induced by Shh and Fgf8
Miao LIU, Xiaoyan WU, Jiawei XU, Runming JIN
《医学前沿(英文)》 2009年 第3卷 第1期 页码 61-66 doi: 10.1007/s11684-009-0007-8
RESPONSE OF WHEAT COMPOSITE CROSS POPULATIONS TO DISEASE AND CLIMATE VARIATION OVER 13 GENERATIONS
《农业科学与工程前沿(英文)》 2021年 第8卷 第3期 页码 400-415 doi: 10.15302/J-FASE-2021394
Since the F5 (2005), three winter wheat composite cross populations (CCPs) based on germplasm specifically suitable for low-input conditions were subjected to natural selection under organic and conventional management. In the F6, each CCP was divided into two parallel populations (12 CCPs in total) and maintained continuously until 2018. Commonly used modern cultivars with different disease susceptibilities were grown alongside to assess the agronomic performance of the CCPs. The organically managed CCPs were comparable in yield and foliar disease resistance to two continuously used reference cultivars, Achat and Capo. In contrast, under conventional management the cv. Capo outyielded the CCPs (Achat was not tested), highlighting the importance of parental cultivar choice for specific management systems. The CCPs were found to be moderately resistant to brown rust and even to the newly emerged stripe rust races prevalent in Europe since 2011. Differences between the CCPs were mainly due to parental genetic background and were significant in the first five generations, but were no longer so in the last five generations. In addition, these differences tended to vary depending on the experimental year and the environmental stresses present. In conclusion, the CCPs despite being derived from older cultivars are able to compete with more recently released reference cultivars under organic farming practices and represent a dynamic germplasm resource.
关键词: evolutionary breeding heterogeneous crop population management system
《环境科学与工程前沿(英文)》 2022年 第16卷 第4期 doi: 10.1007/s11783-021-1475-6
• The concentrations of 13 heavy metals in Taihu Lake were analyzed.
关键词: Heavy metals Human health ambient water quality criteria Taihu Lake Health risk assessment Contribution rate
Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology
null
《医学前沿(英文)》 2013年 第7卷 第1期 页码 25-30 doi: 10.1007/s11684-013-0244-8
Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor family. It actually functions as endocrine hormones but does not regulate cell growth and differentiation. It is demonstrated that FGF21 acts on multiple tissue to coordinate carbohydrate and lipid metabolism, including enhancing insulin sensitivity, decreasing triglyceride concentrations, causing weight loss, ameliorating obesity-associated hyperglycemia and hyperlipidemia. Moreover, FGF21 also plays important roles in some physiological processes, such as fasting and feeding, growth hormone axis and thermogenic function of brown adipose tissue. Clinical relevance of FGF21 in humans is still unclear, and the basis and consequences of increased FGF21 in metabolic disease remain to be determined. Both the pharmacological actions and physiological roles make FGF21 attractive drug candidates for treating metabolic disease, but some questions remain to be answered. This article concentrates on recent advances in our understanding of FGF21.
关键词: FGF21 metabolism pharmacology physiology clinical relevance
Qing YE, Donghui LI, Jun ZHAO, Jiansheng ZHAO, Tianfang KANG, Shuiyuan CHENG
《环境科学与工程前沿(英文)》 2011年 第5卷 第4期 页码 497-504 doi: 10.1007/s11783-011-0256-z
关键词: 13X-type zeolite CO oxidation gold solution pH calcination temperature
Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran
null
《医学前沿(英文)》 2016年 第10卷 第3期 页码 345-350 doi: 10.1007/s11684-016-0462-y
Asthma is the most common chronic disease among children, and its incidences are often imminent among elementary schoolchildren. This study aimed to examine the prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran. The prevalence rate was compared according to age group (aged 6–7 years vs. aged 13–14 years) and gender (male vs. female). In this cross-sectional study, 1706 Iranian schoolchildren aged 6–7 and 13–14 years in Golestan Province were enrolled. Participants completed questionnaires between February and July 2014. Asthma symptoms were assessed using the questionnaire of the International Study of Asthma and Allergies in Childhood protocol in Persian. The logistic regression model was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) of the asthma symptoms for each of the gender and age groups. The prevalence rates of “current asthma” symptoms and “asthma ever” in all the children were estimated as 9.5% and 7.5%, respectively. The prevalence of asthma (“asthma ever” and “wheezing in the past 12 months”) in junior high schoolchildren (aged 13–14 years) is higher than that in elementary schoolchildren (aged 6–7 years) (P <0.05). The prevalence of the severity of wheezing in girls is lower than that in boys (OR= 1.7, 95%CI= 1.06–2.96, P = 0.02). Asthma is still a major public health problem. This study shows that the prevalence of the asthma symptoms in boys is lower than that in girls in both age groups, and the severity of asthma in girls is higher than that in boys aged 13–14 years.
关键词: asthma asthma symptoms epidemiology childhood chronic disease
Separating method and dynamic processes of Nano-Al13
GAO Baoyu, YUE Qinyan, WANG Xiaona, CHU Yongbao, KONG Chunyan
《环境科学与工程前沿(英文)》 2007年 第1卷 第3期 页码 368-373 doi: 10.1007/s11783-007-0063-8
关键词: displacement PAC coagulation efficiency poly-aluminum inorganic
A novel method for reconstruction in laparoscopic pancreaticoduodenectomy: an experience of 13 cases
LU Bangyu, HUANG Yubin, CAI Xiaoyong, HUANG Fei, LU Wenqi, XU Jing, LIU Zujun, YAN Yihe, LI Jianjun, LI Jie
《医学前沿(英文)》 2007年 第1卷 第4期 页码 369-372 doi: 10.1007/s11684-007-0071-x
关键词: alimentary dunking pancreaticojejunostomy challenging operation anastomosis success
“养殖业十三五规划战略研究”项目组
《中国工程科学》 2016年 第18卷 第1期 页码 17-21 doi: 10.15302/J-SSCAE-2016.01.003
“十三五”期间乃至未来一段时间内,我国养殖产品需求仍呈刚性增长,但是养殖业面临资源短缺日趋严重、环境制约日益加剧等不利局面,同时面临国际竞争对国内产业冲击加剧等新的形势,未来我国养殖业必须走可持续发展道路。本文基于对我国养殖业的发展现状、可持续发展所面临的挑战,形成对我国养殖业可持续发展形势的基本判断,针对“十三五”,凝练了养殖业可持续发展的战略目标、基本原则和战略重点,并提出了“进一步明确养殖业在现代农业中的战略主导地位”“合理利用国际市场保障我国食物安全”“加快启动和实施一批养殖科技重点研发计划”等重大建议,为我国养殖业加快发展方式转变、实现现代化提供理论支撑。
舒俭民,张林波,罗上华,杜加强,梁广林
《中国工程科学》 2015年 第17卷 第8期 页码 39-45
十三五”时期是我国加快推进生态文明建设、全面建成小康社会的关键时期。基于对生态文明建设面临的八大重要挑战的总体判断,提出了“十三五”时期生态文明建设目标和指标建议,提出了生态文明建设的九大重点任务,包括实施绿色拉动战略驱动产业转型升级、提高资源能源效率建设节约型社会、以重大工程带动生态系统量质双升、着力解决危害公众健康的突出环境问题、划定并严守生态保护红线体系、推进新型城镇化战略统筹城乡发展、开展国家生态资产家底清查核算与监控评估平台建设、全面开展全民生态文明新文化活动、实施生态文明工程科技支撑重大专项;最后提出了五项保障的条件与政策建议。
Xiaofang Cui, Benting Ma, Yan Wang, Yan Chen, Chunling Shen, Ying Kuang, Jian Fei, Lungen Lu, Zhugang Wang
《医学前沿(英文)》 2019年 第13卷 第1期 页码 104-111 doi: 10.1007/s11684-017-0568-x
关键词: retinol dehydrogenase 13 carbon tetrachloride acute liver injury Cyp2e1 Spot14
ARC-13-009716-01)
Maiquel DE BRITO,Lauren THÉVIN,Catherine GARBAY,Olivier BOISSIER,Jomi Fred HÜBNER
《信息与电子工程前沿(英文)》 2016年 第17卷 第4期 页码 309-324 doi: 10.1631/FITEE.1500369
关键词: Situated artificial institutions (SAIs) Normative system Tangible interaction Crisis management
标题 作者 时间 类型 操作
Influence of retinoic acid on TBX1 expression in myocardial cells induced by Shh and Fgf8
Miao LIU, Xiaoyan WU, Jiawei XU, Runming JIN
期刊论文
RESPONSE OF WHEAT COMPOSITE CROSS POPULATIONS TO DISEASE AND CLIMATE VARIATION OVER 13 GENERATIONS
期刊论文
Human health ambient water quality criteria for 13 heavy metals and health risk assessment in Taihu Lake
期刊论文
Low-temperature CO oxidation over Au-doped 13X-type zeolite catalysts: preparation and catalytic activity
Qing YE, Donghui LI, Jun ZHAO, Jiansheng ZHAO, Tianfang KANG, Shuiyuan CHENG
期刊论文
Prevalence of asthma symptoms in Golestan schoolchildren aged 6–7 and 13–14 years in Northeast Iran
null
期刊论文
Separating method and dynamic processes of Nano-Al13
GAO Baoyu, YUE Qinyan, WANG Xiaona, CHU Yongbao, KONG Chunyan
期刊论文
A novel method for reconstruction in laparoscopic pancreaticoduodenectomy: an experience of 13 cases
LU Bangyu, HUANG Yubin, CAI Xiaoyong, HUANG Fei, LU Wenqi, XU Jing, LIU Zujun, YAN Yihe, LI Jianjun, LI Jie
期刊论文
Rdh13 deficiency weakens carbon tetrachloride-induced liver injury by regulating Spot14 and Cyp2e1 expression
Xiaofang Cui, Benting Ma, Yan Wang, Yan Chen, Chunling Shen, Ying Kuang, Jian Fei, Lungen Lu, Zhugang Wang
期刊论文